1568P Physical condition in patients with a recent diagnosis of colorectal cancer

Assessment of physical condition (PC) is utmost interest for physicians and specifically medical oncologists, since it highly informative the process therapeutic decision-making. PC ability to carry out daily tasks with vigour alertness, without undue fatigue ample energy engage in leisure time pursuits meet above-average stresses encountered emergency situations. The concept includes different components: (a) body composition, (b) cardiorespiratory component, (c) muscular component (muscular strength endurance), (d) motor (balance, flexibility, speed). To identify differences patients (pts) localized metastatic diseases at diagnosis. Pts a recent diagnosis colorectal cancer (CRC) who were able walk mile evaluated hospital setting. Body composition was through BMI, Rockport test which estimates VO2max Kline formule, dynamometry (hand-grip) “sit stand” walking speed both one-mile (OMWT) six-minute (SMWT). 188 pts recruited. Mean age 65 (25-88), (125 male/63 female) included. 111 stage II-III/ 77 IV.Table: 1568PBMIBasal heart rateRockport testWalking speedMuscular strength(kg/m2)(beats per minute)VO2max (ml/kg/min)Time one (min)Distance 6 minutes (meters)Upper Dyn (Kg)Lower STS (seg)Total26.876.124.217.255732.07,8Localized26.774.926.216.754532.27,9Metastatic27.078.220.818.056431.87.7p-valuens0.0470.000.008nsnsns Open table new tab Objective evaluation feasible disease but does not affect equally all components PC. Whereas much poorer patients, BMI are similar groups. SMW could be insufficient stratifying population respiratory or lung cancer. OMWT sensitive used as an additional tool select aggressive therapies.